Work

Rational Fabrication of Copper Nanoclusters and In Vitro Study of Antioxidant Property

Year: 2025

Type: article

Abstract: Oxidative stress, resulting from an imbalance between reactive oxygen species (ROS) and antioxidants, is a critical factor in the pathogenesis of a wide range of diseases. The excessive accumulation of ROS can cause severe cellular damage, leading to tissue dysfunction and disease progression. The development of nanomaterials with antioxidant properties presents a promising strategy for addressing this challenge. Herein, we report the fabrication of albumin-biomineralized copper nanoclusters (BCNCs) as a novel antioxidant platform and evaluate their effectiveness in combating oxidative stress. Our results show that BCNCs exhibit potent ROS scavenging abilities and protect cells from oxidative stress-induced damage, highlighting their potential as an effective therapeutic strategy for oxidative stress-related diseases.

Source: Nanomaterials

DOI: 10.3390/nano15050360

Authors: Jiale Zhang, Xiao Liang, Mijia Yan, Qiuhong Zhang, Hangrong Chen

Institutions: Chinese Academy of Sciences, Shanghai Institute of Ceramics, University of Chinese Academy of Sciences, State Key Laboratory of High Performance Ceramics and Superfine Microstructure

Language: English

Topic: Nanocluster Synthesis and Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896