Work

Suspected autoimmune-mediated dissociative symptoms

Year: 2025

Type: article

Abstract: Dissociative disorders are usually interpreted as psychoreactive sequelae of stressful life events or conflicts that patients may avoid through symptoms [ 1 ]. Dissociative symptoms can occur in other mental disorders, such as borderline personality disorder, learning disability, autism spectrum disorder, or schizophrenia. Little is known about secondary forms and their underlying biological mechanisms. Therefore, this paradigmatic case study of a patient with predominant dissociative symptoms and associated novel anti-central nervous system (CNS) antibodies in the cerebrospinal fluid (CSF) is presented.

Source: Molecular Psychiatry

DOI: 10.1038/s41380-025-02926-0

Authors: Dominique Endres, Elena Reinhold, Christian Klesse, Katharina Domschke, Harald Prüss, Ludger Tebartz van Elst