Work

Synchronous Minimally Invasive Resection of Carcinomas of Lung and Esophagus After Downstaging by Palliative Immunotherapy

Year: 2025

Type: article

Abstract: We report a case of an elderly patient with synchronous locally advanced bilateral lung and esophageal adenocarcinomas downstaged by atypical multimodality induction therapy. A short course of palliative immunotherapy (stopped for complications after 2 cycles), followed by stereotactic lung irradiation and later neoadjuvant fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy, allowed subsequent synchronous minimally invasive combined esophagectomy and anatomical lung resection with excellent outcome. This report further illustrates the technical feasibility of minimally invasive synchronous anatomical lung and esophagus resection after multimodal therapy, including immunotherapy.

Source: Annals of Thoracic Surgery Short Reports

DOI: 10.1016/j.atssr.2025.01.024

Authors: Robbe Van Dyck, Bob Edon, Thierry Wagner, Sven Philippi, Flaviu Crisan, Georges Decker

Institutions: Centre François Baclesse, Laboratoire National de Santé

Language: English

Topic: Esophageal Cancer Research and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $975