Ultrasound-assisted Thrombolysis Therapy for the Treatment of Acute Pulmonary Embolism in an Intermediate-high-risk Patient With Multiple Comorbidities: a Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Venous thromboembolism is an event that occurs within two components: deep venous thrombosis and pulmonary embolism. With many risk factors including old age, hospitalization and recent surgeries, malignancies, and the use of oral contraceptives, it occurs to be a relatively common condition. The European Society of Cardiology divides patients with acute pulmonary embolism into high-risk pulmonary embolism, low-risk pulmonary embolism, intermediate-high-risk pulmonary embolism, and intermediate-low-risk pulmonary embolism. This division is made based on three main criteria: hemodynamic stability, right ventricular dysfunction, and elevated troponin levels. Patient management based on risk stratification plays a vital part during the treatment. A 57-year-old woman arrived at the emergency department with syncope, abrupt shortness of breath, and unusual pleuritic chest pain. The patient had hypertension, insulin-dependent diabetes mellitus, and coronary artery disease dating back to 2012, which began with an anterior myocardial infarction treated with a left anterior descending stent. The patient later required additional stents in the left coronary artery and circumflex artery due to restenosis. At the date of approach, a three-vessel coronary artery bypass graft procedure was performed on her a month ago. With this medical history and being assessed as an intermediate-high-risk group, she was considered a candidate for catheter-directed therapy. Ultrasound-assisted thrombolysis therapy was performed with EkoSonic® Endovascular System and the patient was discharged with a total cure. This case serves as an example regarding the issue of a proper approach to patient management.
Source: TURKISH MEDICAL STUDENT JOURNAL
Authors: Ayan Mammadova, Myas Murad
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407970146