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A Pelvic Mass in a Young Patient With Crohn's Disease

Year: 2025

Type: article

Abstract: Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD. We report a rare case of coexisting unicentric Castleman disease in a young patient with Crohn's disease.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000001627

Authors: Charles D. Evers, Aishwarya Ravindran, Frida Rosenblum, Frederick Weber

Institutions: University of Alabama at Birmingham, UAB Medicine

Language: English

Topic: Lymphadenopathy Diagnosis and Analysis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4407970975

FWCI:

Cites: 17

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Related to: 10