Work

Molecular Diffusion and Optical Properties of Implantable Collagen Materials

Year: 2025

Type: article

Abstract: The effects of optical clearing of implantable collagen materials were studied using optical clearing agents (OCAs) based on aqueous glucose solutions of various concentrations. By measuring the kinetics of the collimated transmission spectra, the diffusion D and permeability P coefficients of the OCAs of collagen materials were determined as D = (0.22 ± 0.05) × 10−6 to (1.41 ± 0.05) × 10−6 cm2/c and P = (0.55 ± 0.04) × 10−4 to (1.77 ± 0.07) × 10−4 cm/c. Studies with optical coherence tomography (OCT) confirmed that each of the OCAs used had an effect on the optical properties of collagen materials, and allowed us to quantify the group refractive indices of the collagen of various samples, which turned out to be in the range from nc = 1.476 to nc = 1.579.

Source: Materials

DOI: 10.3390/ma18051035

Authors: Sofya V. Atsigeida, Daria K. Tuchina, Peter S. Timashev, Valery V. Tuchin

Institutions: Saratov State University, National Research Tomsk State University, Sechenov University, Institute of Precision Mechanics and Control, Saratov Research Center

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137