Work

Research progress in Fangjiomics: methodologies, applications, and perspectives

Year: 2024

Type: article

Abstract: Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective. We reviewed recent advances in Fangjiomics, focusing on database and analysis platform development, methodological innovations, and translational applications. Through the integration of Fangji and multi-omics data, multi-level system analysis approaches were developed, encompassing single-target analysis, signaling pathways, multi-targeted network and modules. Fangjiomics has emerged as a key strategy in various areas of Fangji research. To support the high quality development of Fangjiomics, we propose principles and perspectives from the integrated, macro-level, and practical viewpoints.

Source: Digital Chinese Medicine

DOI: 10.1016/j.dcmed.2025.01.001

Authors: Bing Li, Yuwen Zhao, Qikai Niu, Zhong Wang

Institutions: China Academy of Chinese Medical Sciences, Institute of Chinese Materia Medica

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $980

Funder: National Natural Science Foundation of China