Work

Adipose derived mesenchymal stem cell-seeded regenerated silk fibroin scaffolds reverse liver fibrosis in mice

Year: 2025

Type: article

Abstract: signaling pathway, which inhibits liver fibrosis, was significantly upregulated in both the RSF and RSF + ADSC groups. Our study suggests that, compared with RSF scaffolds alone, RSF + ADSCs have a significant repair effect on chronic LF in mice.

Source: Journal of Materials Chemistry B

DOI: 10.1039/d5tb00275c

Authors: Weilong Li, Xiaonan Shi, Daxu Zhang, Jingjing Hu, Shuo Zhao, Shujun Ye, Jingyi Wang, Xiaojiao Liu, Qian Zhang, Zhanbo Wang, Yaopeng Zhang, Li Yan

Institutions: Chinese PLA General Hospital, Aerospace Center Hospital, Donghua University, Lanzhou University

Language: English

Topic: Silk-based biomaterials and applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: G1361842606, G7146101054

OpenAlex ID: W4407983475

FWCI: 0.743

Cites: 52

Cited by: 4

Related to: 10