Work

Prognostic factors for recurrence in acquired hemophilia A-results from a long-term observational study

Year: 2025

Type: article

Abstract: Objectives: Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against factor (F)VIII (FVIII), potentially leading to life-threatening bleeding. While predictors for remission have been analyzed, data on recurrence is lacking. Methods: = 23) with at least 1 year of follow-up. Results: = .344). Conclusion: Initial FVIII <1 IU/dL and failure to achieve initial CR are identified as risk factors for recurrence in AHA. Patients with these characteristics should be closely monitored for at least 1 year after initial remission due to increased recurrence risk.

Source: Research and Practice in Thrombosis and Haemostasis

DOI: 10.1016/j.rpth.2025.102707

Authors: Lisa Reich, Florian Gatzke, Steffen Rauchfuss, Stefanie Roth, Wolfgang Miesbach

Institution: University Hospital Frankfurt

Language: English

Topic: Hemophilia Treatment and Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,250