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Low extracellular pH enhances TRAIL-induced apoptosis by downregulating Mcl-1 expression

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Year: 2025
Type: article
Source: Experimental Cell Research
DOI: 10.1016/j.yexcr.2025.114481
Authors: Farzaneh Vafaeinik, Lin Zhang, Yong J. Lee
Institutions: Cedars-Sinai Medical Center, University of Southern California, USC Norris Comprehensive Cancer Center
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Defense, Cedars-Sinai Medical Center, National Institutes of Health, National Cancer Institute, DOD Peer Reviewed Cancer Research Program
Awards: Application of in vivo humanized PDX mouse model and ex vivo organoid model to assess the therapeutic efficacy of combinatorial therapy for pseudomyxoma peritonei, G344966962, G4119534169, G4682382839, G5370247717, G5850682332, G9000021776
OpenAlex ID: W4408028381
FWCI: 0.594
Cites: 30
Cited by: 2
Related to: 10
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