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Pulmonary Hyalinizing Granuloma: A Rare and Challenging Case

Year: 2025

Type: article

Abstract: Hyalinizing Pulmonary Granuloma (HPG) is a rare pseudoneoplastic pulmonary lesion requiring histopathological diagnosis, often challenging for pathologists. We present the case of a 54-year-old woman with an incidental HPG diagnosis. She had a history of urogenital tuberculosis but no prior pulmonary involvement. Macroscopic examination revealed a 35-mm firm nodular lesion, while histology showed eosinophilic, hyalinized lamellae concentrically arranged around blood vessels, interspersed with histiocytes, lymphocytes, and plasma cells. Congo red staining was negative. Pathologists should consider HPG when the morphology is suggestive. Diagnosis of HPG relies on collaboration between pathologists, surgeons, and radiologists.

Source: International Journal of Pathology and Clinical Research

DOI: 10.23937/2469-5807/1510161

Authors: Abderrahmane Mellouki, Imad Jalloul, Salah Mouadib, Mohamed Labied, Mehdi Karkouri, Souhail Boubia, Mohammed Ridai

Institutions: Centre Hospitalier Universitaire Ibn Rochd, University of Hassan II Casablanca

Language: English

Topic: Medical Imaging and Pathology Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4408029701

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