Year: 2024
Type: article
Abstract: The study aims to evaluate some characteristics of platelet-rich plasma (PRP) from umbilical cord blood.Research on 6 umbilical cord blood samples compared with 6 donor venous blood samples, using the GeneWorld kit. The results show that PRP from umbilical cord blood had fewer red blood cells (0.105 (0.07 - 0.17) T/L, 0.32 (0.12 - 0.55), p < 0.01), higher platelet count (701.17 ± 124.75 G/L vs. 457.83 ± 88.95 G/L, p < 0.01) and higher platelet count concentration ratio (2.3 vs. 1.82; p < 0.05). The concentration of EGF in umbilical cord blood plasma was 85.478 ± 28.195 pg/ml, that of healthy donors was 74.973 ± 29.475 (p > 0.05) with VEGF concentrations of 88,090 (67,536 - 135.32) and 10,504 (4,094 - 16,029) pg/mL, respectively, p < 0.05. The EGF concentration in activated PRP from umbilical cord blood and adult blood was 115.72 (50.98 -178.96) pg/mL and 94.91 (50.92 - 159.28) pg/mL (p < 0.05), with VEGF being 281.48 (141.59 - 324.12) pg/mL and 32.6 (11.7 - 53.4) pg/ml, respectively, p < 0.01. In conclusion, umbilical cord blood had normal hematological indices. PRP from umbilical cord blood had fewer red blood cells, higher platelet counts, platelet aggregation ratio, and VEGF concentration than PRP from adult blood. The VEGF concentration in activated PRP from umbilical cord blood was higher than that in adult blood.
Source: Tạp chí Y học Thảm hoạ và Bỏng
Authors: Minh Duc Ngo, Anh Tuan Chu, Xuan Hai Do, Thi Mai Huong Nguyen, Quang Dong Nguyen, Thi Huong Nguyen, Minh Trung Do
Institution: Vietnam Military Medical University
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4408039213