The link between serum vitamin D levels and bronchial asthma: A case control study
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objectives Asthma is a common long-term respiratory condition that considerably increases morbidity worldwide. Because of its immunomodulatory properties, vitamin D may have an impact on the severity of asthma. This case control study explores the relationship between serum vitamin D levels and bronchial asthma. Material and Methods There were 70 participants in all, 35 of whom were matched controls and 35 of whom were asthma patients. Measurements of IgE and serum vitamin D were made to look for associations with asthma. Results Patients with asthma had higher IgE levels, suggesting heightened allergic reaction and substantially less vitamin D in their blood (13.83 ± 9.34 ng/mL) than control (27.34 ± 8.19 ng/mL) (p < 0.001). Conclusion This study highlights that individuals with bronchial asthma tend to have lower serum vitamin D levels and higher IgE levels, suggesting a link between vitamin D deficiency and asthma severity. Addressing vitamin D deficiency may offer a supportive role in asthma management, though further studies are needed to confirm these findings.
Authors: Pavan N Kumar, Amirullah Amirullah, Deepak Kumar R
Institution: Kempegowda Institute of Medical Sciences
Language: English
Topic: Vitamin D Research Studies
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4408042019