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Molecular monitoring of RNA viruses belonging to Orthohantaviridae family circulating among small mammals in two regions of the Russian Federation

Year: 2025
Type: article
Abstract: mortality.Among the VGs, feoB was possessed by 83% of the isolates followed by kpsMTIII (73%), fimH (70%), iutA (59%), and others.The most frequent combination observed was feoB + fimH (68%).However, correlation between 30-day mortality & possession of feoB + fimH combination.was statistically insignificant (p = 0.12).Discussion: The finding of 23% thirty-day mortality in our study was comparable to a similar study from Europe (2021) where the probability of death was 19.5% and.there was a strong positive correlation with the virulence genes.In our study, although majority had single or combination genes but the correlation was not significant which could be due to small sample size.Conclusion: All isolates possessed differentVGs encoding multiple virulence factors and > 50% mortality were associated with feoB + fimH combination.This knowledge may be useful for detecting virulent strains and predicting clinical outcome in E.coli BSI.
DOI: 10.1016/j.ijid.2024.107666
Authors: Mrs Kristina Stolbunova, Dr Olesia Ohlopkova, Mr Igor Popov, Dr Emmanuel Kabwe, Dr Yuri Davidyuk, Ms Marina Stepanyuk, Mr Alexey Moshkin, Dr Yury Yurchenko, Dr Svetlana Khaiboullina, Dr Alexander Shestopalov, Dr Emmanuel Kabwe
Institutions: Indian Council of Agricultural Research, Indian Veterinary Research Institute, Kazan Federal University, Lala Lajpat Rai University of Veterinary and Animal Sciences, State Research Center of Virology and Biotechnology VECTOR, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Russian Academy of Sciences, Institute of Systematics and Ecology of Animals, Siberian Branch of the Russian Academy of Sciences
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,900
OpenAlex ID: W4408046893
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