Year: 2025
Type: article
Abstract: be tested for its bactericidal potential using agar diffusion and broth microdilution assays.Discussion: Scorpion venom peptides have been assessed for their potential to act against a broad range of bacteria including Methicillin resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Bacillus subtilis, Micrococcus luteus, Pseudomonas aeruginosa and E. coli.N. tabacum plant system proves to be a better host system for transient expression of recombinant functional antimicrobial peptides such as protegrin-1.Further optimization, extraction and purification of Meucin18 from N. tabacum will be useful in the development of a broad-spectrum antibacterial laboratory reagent.Conclusion: The purified recombinant AMP Meucin18 from N. tabacum will be an efficient antibacterial agent that could be used against a broad range of bacteria.
Authors: Dr Hang Ding, Mrs Ashley Quigley, Professor Raina MacIntyre
Institutions: UNSW Sydney, Kirby Institute
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,900
OpenAlex ID: W4408046953