Dragonfly Molecular Diagnostic Platform: A Rapid Point-of-Care Solution for Monkeypox and Skin Lesion Pathogens
Year: 2025
Type: article
Abstract: be tested for its bactericidal potential using agar diffusion and broth microdilution assays.Discussion: Scorpion venom peptides have been assessed for their potential to act against a broad range of bacteria including Methicillin resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Bacillus subtilis, Micrococcus luteus, Pseudomonas aeruginosa and E. coli.N. tabacum plant system proves to be a better host system for transient expression of recombinant functional antimicrobial peptides such as protegrin-1.Further optimization, extraction and purification of Meucin18 from N. tabacum will be useful in the development of a broad-spectrum antibacterial laboratory reagent.Conclusion: The purified recombinant AMP Meucin18 from N. tabacum will be an efficient antibacterial agent that could be used against a broad range of bacteria.
Authors: Dr Kenny Cardenas, Dr Matthew Cavuto, Dr Marcus Pond, Dr Ivana Pennisi, Mr Sohail Mirza, Mr Mark Comer, Dr Isobel Stokes, Dr Sian Lant, Dr Rebecca P Sumner, Dr Luca Miglietta, Dr Frankie Bolt, Prof Alison Holmes, Prof Shiranee Sriskandan, Dr David O Ulaeto, Dr Carlos Maluquer de Motes, Dr Jesus Rodriguez-Manzano
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,900
OpenAlex ID: W4408047032