Work

Evaluation of Multimerization of Aptamers against SARS-CoV-2 Delta Variant VLP as A Refinement Strategy in The Detection of the SARS-CoV-2 Virus

Year: 2025

Type: article

Abstract: pg/ml; R2: 0.99), with recovery and reproducibility within the acceptable range, and a low limit of quantification of 1 pg/ml.Discussion: Both the Mabtech Flex and Pro bovine IFN-γ ELISA assays are deemed suitable for measuring bison IFN-γ , offering flexibility depending on available resources.These findings indicate the potential of IFN-γ assays as a diagnostic tool for detecting M. bovis infection in bison populations, contributing to effort s in disease management and conservation. Conclusion:The evaluation of commercial IFN-γ ELISA assays provides valuable insights further validation is warranted to calculate the assay's cut-off value to confirm their ability to differentiate between M. bovis-infected and uninfected bison to support their role in effective disease surveillance and control measures in bison populations.

Source: International Journal of Infectious Diseases

DOI: 10.1016/j.ijid.2024.107584

Authors: Dr Siti Farah Nawi, Mr Amir Muhaimin Akmal Shukri, Assoc Prof Dr Wang Seok Mui, Assoc Prof Dr Chia Suet Lin, Dr Citartan Marimuthu

Institutions: Universiti Teknologi MARA System, Universiti Teknologi MARA, Universiti Sains Malaysia

Language: English

Topic: SARS-CoV-2 detection and testing

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,900