Clinical case of Gorham – Stoat syndrome
Year: 2025
Type: article
Study design: Case Report
Abstract: Disappearing bone disease, or Gorham – Stoat syndrome, is a disease of massive osteolysis associated with the proliferation of hemangiotic tissue leading to bone resorption. Material and methods. The article presents a rare clinical case of Gorham – Stoat syndrome in a 19-year-old patient. The disease manifested at the age of 16 with a lesion of the thoracic vertebrae. Results. Against the background of the appearance of neurological disorders due to compression of the spinal cord and the development of myelopathy, the patient initially required surgical treatment on the spine. The diagnosis of massive osteolysis is based on anamnesis, X-ray data and histological conclusion. Subsequently, multiple lesions of the ribs, pelvic bones and skull were added. Quite rare in this case is a multi-focal lesion of the skull bones with compression of brain structures. Conclusions. In differential diagnosis against the background of multifocal resorption of skeletal and cranial bones, it is important to remember about etiological causes that are rarer than hematological and metastatic lesions, including idiopathic osteolysis.
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408056605