Work

Segmental Congenital Vascular Anomaly With Atrophy, Ulceration and Scarring With Complications in Pregnancy

Year: 2025

Type: article

Abstract: A 33-year-old woman with a segmental non-involuting congenital vascular anomaly of the left neck developed pain and ulceration in pregnancy and left-sided Horner's syndrome after delivery. Mutational analysis of affected tissue showed a missense mutation in GNA11 (Glu209) and a second mutation in PIK3CA. Sirolimus therapy resulted in healing of the ulceration and resolution of the Horner's syndrome.

Source: Australasian Journal of Dermatology

DOI: 10.1111/ajd.14441

Authors: Anne R. Halbert, AmyLeigh Hall, Cathryn Poulton

Institutions: The University of Western Australia, Sir Charles Gairdner Hospital, King Edward Memorial Hospital

Language: English

Topic: Vascular Malformations and Hemangiomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,160