Natural Chemical Constituents and Polymer Used in to Reduce PCOS Pain
Year: 2025
Type: article
Abstract: The complex metabolic and endocrine disorder known as polycystic ovarian syndrome (PCOS) is characterised by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries. Factors that predispose women to polycystic ovarian syndrome encompass dietary and lifestyle decisions, environmental pollutants, genetic predisposition, gut dysbiosis, alterations in neuroendocrine function, and excess adiposity. Hyperinsulinemia, oxidative stress, hyperandrogenism, inadequate folliculogenesis, and irregular menstrual periods are symptoms that may arise from these variables, potentially contributing to an escalation of metabolic syndrome. Pathogenic dysbiosis of the gut microbiota may have a role in the aetiology of polycystic ovarian syndrome (PCOS). Immature oocytes, insulin resistance, hyperandrogenism, inflammation, oxidative stress, and resveratrol are pathological features of PCOS that may be ameliorated by supplementation with natural compounds such as polyphenols, quercetin, resveratrol, flavonoids, vitamin C, gamma-linolenic acid, piperine, and omega-3 fatty acids, along with natural and semi-synthetic polymers. This review encapsulates the current understanding of the efficacy of natural chemical supplementation in the treatment of PCOS.
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408076419