Work

Thalidomide as Treatment of Lip’s Pyogenic Granuloma

Year: 2025

Type: article

Abstract: Pyogenic granuloma (PG) is a benign vascular tumor that can be challenging to treat, particularly in aesthetically sensitive areas. We report a case of a 32-year-old man with a PG on the upper lip that did not respond to conventional treatments, including glucocorticoid injections and long-pulse 1064 nm laser therapy. Due to aesthetic concerns and the lack of response to these treatments, the patient was administered oral thalidomide at a nightly dose of 75 mg for 5 months, which resulted in complete regression without recurrence over a 3-year follow-up. This case suggests thalidomide's potential as an effective alternative treatment for PG in sensitive areas.

Source: International Medical Case Reports Journal

DOI: 10.2147/imcrj.s511053

Authors: Liyan Lai, Jiayao Nie, Dejian Duan, Dan Huang

Institutions: Guangzhou University of Chinese Medicine, Shenzhen Traditional Chinese Medicine Hospital

Language: English

Topic: Vascular Malformations and Hemangiomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,320