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Sphenoid Sinus Adenoid Cystic Carcinoma: Navigating Uncharted Territory with a Spotlight on the Crucial Role of Radiotherapy

Year: 2025
Type: article
Study design: Case Report
Abstract: A BSTRACT Adenoid cystic carcinoma (ACC) arising from the sphenoid sinus poses unique challenges in management due to its proximity to critical structures and late-stage presentations. We herein detail a rare case of a 46-year-old female with ACC originating from the sphenoid sinus, manifesting as progressive left-eye vision loss. After decompressive surgery, the patient received radical radiotherapy (RT), leading to significant recovery in left ptosis and improved vision in the right eye. The effectiveness of RT in treating ACC remains a topic of debate, as evidenced by divergent opinions in the literature, with only 20 comparable cases documented in English literature. This rare case provides valuable insights into the management of ACC arising from the sphenoid sinus, underscoring the pivotal role of radical RT in situations where surgical intervention alone proves inadequate.
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4408088826
FWCI:
Cites: 9
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Related to: 10