Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Year: 2025
Type: supplementary-materials
Abstract: Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. Genes that were indicated as common essential by DepMap were removed from this list. Table S2A. GSEA Pathway analysis from datasest in Figure 2I (day 28). Table S2B. GSEA Pathway analysis from datasest in Figure 2I (day 49). Table S2C. GSEA Pathway analysis from datasest in Figure 2I (day 91). Table S3. Number of motifs 10kbp from MHC Class I processing genes that were targeted by a small library CRISPR screen. Table S4A. GSEA Pathway analysis from dataset in Figure 4A. Table S4B. GSEA Pathway analysis from dataset in Figure 4A. Table S5A. GSEA Pathway analysis from dataset in Figure 4B. Table S5B. GSEA Pathway analysis from dataset in Figure 4B. Table S6: List of sgRNA sequences. Table S7: List of qRT-PCR primer sequences.
Authors: Lisa N. Chesner, Fanny Polesso, Julie N. Graff, Jessica E. Hawley, Alexis K. Smith, Arian Lundberg, Rajdeep Das, Tanushree Shenoy, Martin Sjöström, Faming Zhao, Ya-Mei Hu, Simon Linder, William S. Chen, Reed M. Hawkins, Raunak Shrestha, Xiaolin Zhu, Adam Foye, Haolong Li, Lisa M. Kim, Megha Bhalla, Thomas O’loughlin, Duygu Kuzuoglu-Ozturk, Junjie T. Hua, Michelle L. Badura, Scott Wilkinson, Shana Y. Trostel, Andries M. Bergman, Davide Ruggero, Charles G. Drake, Adam G. Sowalsky, Lawrence Fong, Matthew R. Cooperberg, Wilbert Zwart, Xiangnan Guan, Alan Ashworth, Zheng Xia, David A. Quigley, Luke A. Gilbert, Felix Y. Feng, Amy E. Moran
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4408094181