Spectrofluorimetric Technique Creation and Approval for Cabotegravir Estimate in Dose Formats for Medications
Year: 2025
Type: article
Abstract: The current investigation sought to create and approve specific spectrofluorimetric technique to cabotegravir estimate in dose formats for medications. The relative fluorescence intensity for the cabotegravir was measured at a wavelength of excitation of 395nm and wavelength of emission at 484nm. There was a linear response with a correlation coefficient of 0.999 between 5 and 25µg/ml. Developed technique was supported with the various validation parameters such as accuracy, sensitivity, specificity, and precision in keeping with the ICH recommendations. The devised approach was shown to be sensitive, the corresponding quantification and detection limits of 0.6 µg/ml and 0.21 µg/ml. The found results indicates the method developed for the estimation of cabotegravir were specific, accurate, precise and reproducible. Finally, it can be concluded that this spectrofluorimetric method could be used in routine analysis for cabotegravir estimate in dose formats for medications.
Source: Oriental Journal Of Chemistry
DOI: 10.13005/ojc/410126
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4408095263