Work

On interrogating electron microscopy images to discover proteins in the cell

Year: 2025

Type: article

Abstract: Interrogating individual two-dimensional (2D) cryo-EM images for the presence of defined three-dimensional (3D) structures that correspond to previously known (or predicted) macromolecular complexes is very challenging, but offers attractive opportunities for the analysis of large numbers of specimens. The work of Zhang et al. [(2025), IUCrJ, 12, 155-176] represents a significant step forward towards this goal.

Source: IUCrJ

DOI: 10.1107/s2052252525001861

Author: Jose-Maria Carazo

Institutions: Consejo Superior de Investigaciones Científicas, Centro Nacional de Biotecnología

Language: English

Topic: Advanced Electron Microscopy Techniques and Applications

Subfield: Structural Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,200

OpenAlex ID: W4408111479

FWCI:

Cites: 9

Cited by:

Related to: 10