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Embryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnostics

Year: 2024

Type: article

Abstract: Female adnexal tumor of Wolffian origin is an extremely rare and poorly studied tumor arising from remnants of Wolffian (mesonephric) duct and having an ambiguous malignancy potential. Immunohistochemical diagnostics of these tumors is important to exclude other pathologies. Interpretation of the prognosis is ambiguous. There are no clear standards for surgical or chemotherapeutic treatment. This is due to the lack of a sufficient number of observations and clinical studies. The article presents a clinical case of Wolffian duct tumor diagnosed in a 75-year-old patient, with a discussion of the terminological, morphological, immunohistochemical and molecular genetic features of the tumor.

Source: Tumors of female reproductive system

DOI: 10.17650/1994-4098-2024-20-4-139-147

Authors: A. B. Villert, O. A. Bondyreva, S. V. Vtorushin, L. A. Kolomiets, M. O. Ochirov, A. A. Maltseva, S. A. Villert

Institutions: Russian Academy of Sciences, Tomsk National Research Medical Center, Siberian State Medical University, Ministry of Health of the Russian Federation

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408113934

FWCI:

Cites: 47

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Related to: 10