Work

Haemophagocytic lymphohistiocytosis driven by disseminated Mycobacterium haemophilum infection

Year: 2025

Type: article

Abstract: Mycobacterium haemophilum is a nontuberculous mycobacteria that primarily affects immunocompromised patients. It can lead to a wide variety of clinical manifestations including infections of the skin, soft tissue and joints. Due to the significant heterogeneity in clinical presentation and difficulty isolating the organism, diagnosis can be difficult and is often delayed. Our patient’s course was further complicated by the development of haemophagocytic lymphohistiocytosis (HLH). Although M. tuberculosis infection is recognized as a potential association, HLH driven by a disseminated M. haemophilum infection has not yet been reported. Here we present a case of disseminated M. haemophilum infection in an immunocompromised patient who developed haemophagocytic lymphohistiocytosis.

Source: Skin Health and Disease

DOI: 10.1093/skinhd/vzae020

Authors: Parissa Irom, Ivan Rodriguez, Paige Kingston, Yasmin Gutierrez, Scott Worswick

Institution: University of Southern California

Language: English

Topic: Mycobacterium research and diagnosis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,597