Alternatives to hormonal therapies in the prevention and correction of dishormonal disorders in women (Part I)
Year: 2025
Type: article
Abstract: Dyshormonal disorders and their comorbid consequences in women of different ages are an urgent problem of today. Hypoestrogenism is a syndrome caused by a decrease in estrogen level. Estrogen deficiency can occur at different ages and is a physiological phenomenon in women in menopause. This is due to the stop of the ovary secretory activity, which are most responsible for the synthesis of estrogens.Pathological causes of estrogen deficiency: damage or surgical removal of the ovaries; polycystic ovary syndrome; premature ovarian failure syndrome; excessive physical activity; pathological changes in the pituitary gland; thyroid dysfunction; eating disorders (anorexia nervosa, bulimia); malnutrition, in particular caused by extreme diets; genetically determined pathology – Turner syndrome; some autoimmune diseases; chronic kidney disease; condition after chemotherapy.Restoring hormone balance allows not only to realize and save the reproductive potential, improve the quality of woman’s life, but also to prevent the development of somatic pathology and ensure active longevity.Phytotherapy is a significant important argument in the correction of estrogen deficiency in a woman’s organism: during menopause or in other conditions accompanied by a decrease in estrogen levels. The main advantages of the phytocomplex are presented in the article. This phytocomplex contains extracts of evening primrose, common fennel seeds, common vitex, hypnotic withania, garden ginger, cimicifuga grape-like, as well as B vitamins, vitamins E, D, iron, magnesium, nicotinic acid and has the ability to comprehensively and personalizedly affect dyshormonal manifestations and several symptoms at the same time, it is easy to use (one tablet per day), has favorable safety profile, especially in the presence of medical contraindications to hormone therapy.Women’s health care should include a paradigm of a personalized preventive and therapeutic model that shapes the duration and quality of a woman’s life. The therapeutic approach to the management of patients with hormonal disorders has a dual but consistent goal: to eliminate the initial symptoms/complaints and reduce long-term adverse risks/outcomes. The transition to personalized medicine requires not only a deep understanding of the pathophysiological changes in women’s organism in the presence of hormonal disorders, but also practical awareness of clinicians regarding the availability of new and effective preventive and therapeutic resources and opportunities.
Source: Reproductive health of woman
Institutions: Shupyk National Healthcare University of Ukraine, National Academy of Medical Sciences of Ukraine, State Institution "Ukrainian Center of Maternity and Childhood of the National Academy of Medical Sciences of Ukraine", Bogomolets National Medical University, National Pirogov Memorial Medical University, Vinnytsya
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408155270