Work

Case Report: Heart Transplantation for Refractory Candida tropicalis Endocarditis: A Case Report and Literature Review

Year: 2025

Type: article

Abstract: prosthetic valve endocarditis refractory to standard antifungals (anidulafungin and fluconazole) and high-dose caspofungin was successfully treated with heart transplantation. The literature review revealed a few cases of bacterial endocarditis successfully treated with heart transplantation, but with only two transplanted cases of fungal endocarditis. This report explores heart transplantation as a last resort for managing refractory infective endocarditis. The patient is still alive and free of infection, two and a half years after transplantation.

Source: Microorganisms

DOI: 10.3390/microorganisms13030580