FDG PET Detection of Neurolymphomatosis in Diffuse Large B-cell Lymphoma, With Neuropathy as Presenting Complaint
Year: 2025
Type: article
Study design: Case Report
Abstract: Two patients with neurolymphomatosis as the initial manifestation of diffuse large B-cell lymphoma are presented. Both patients experienced mixed severe sensorimotor neuropathy as their presenting complaint. Subsequently, both had a prolonged interval to diagnosis, 6 and 14 months, respectively. MRI or CT imaging in both cases was nondiagnostic, and FDG PET/CT was used to demonstrate intense uptake throughout spinal nerves, leading to biopsy and definitive diagnosis. FDG PET/CT is a valuable investigation that should be considered early in cases of intractable progressive neuropathy to eliminate malignant differential causes.
Source: Clinical nuclear medicine open.
Authors: Kersandra Begley, Richard Quinn
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4408157883