To Compare Efficacy and Safety of Intravenous Nitroglycerine with Topical Nitroglycerine [ORAL NTG SPRAY] During Laryngoscopy and Intubation
Year: 2025
Type: article
Abstract: Hypertension and tachycardia following tracheal intubation can lead to serious complications such as myocardial ischemia and increased intracranial pressure. Various agents, including nitroglycerin (NTG), have been used to attenuate these hemodynamic responses. This study evaluates the efficacy of intravenous (IV) and oral transmucosal NTG spray in mitigating pressor responses during laryngoscopy and intubation. Results indicate that both forms of NTG effectively prevent significant increases in blood pressure while causing transient tachycardia. Findings align with previous research, suggesting NTG as a viable option for hemodynamic stabilization during intubation.
Authors: Jigneshkumar L Parmar, Zakiyabegum Saiyed, Jyotsna Baria, Saumil Shah, Sejal Kalara, Vismit Gami
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408160503