Work

Use of Epilobium parviflorum in the Treatment of Benign Prostatic Hyperplasia in Canines

Year: 2025

Type: article

Abstract: ABSTRACT The objective of the study was to evaluate the effect of Epilobium parviflorum (EP) as a treatment for benign prostatic hyperplasia (BPH) in dogs based on two clinical case reports. Two dogs with BPH were treated for 2 months with EP extract. For both cases, follow‐up was performed with B‐mode ultrasound on Days 7, 15, 30 and 60 after starting treatment, and measurements of the length, width and height of the prostate were taken to calculate its volume (cm 3 ). A complete blood count, liver and kidney biochemistry, urinalysis and serum testosterone concentration (ng/dL) were completed at the same time points. EP was well tolerated with no side effects observed during the 60‐day oral administration period. In both cases, prostate volume decreased by 40% (Case 1: 81–50 cm 3 ; Case 2: 79–44 cm 3 ) by Day 60. Serum testosterone concentration decreased by 30% for Case 1 (749–512 ng/dL) and 20% for Case 2 (220–188 ng/dL). This case report describes an alternative therapeutic method effective for treating canine BPH without apparent adverse reactions or complications.

Source: Veterinary Medicine and Science

DOI: 10.1002/vms3.70205

Authors: Guillermo Cazzuli, Juan Pablo Damián, Lucía Minini, Fernando Ferreira, Gonzalo Suárez, Paula Pessina

Institution: Universidad de la República de Uruguay

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,880