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Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease

Year: 2025

Type: article

Abstract: Immunoglobulin A vasculitis (IgAV) is an immune-mediated disorder that commonly involves dermatologic, musculoskeletal, renal, and gastrointestinal systems. Drug-induced cases of IgAV are rare and sparsely documented in the literature. We report a case of a patient with Crohn's disease who developed a tender, palpable purpuric rash on the torso and extremities 3 weeks after receiving a dose of ustekinumab. This case underscores the importance of considering IgAV in patients with inflammatory bowel disease who present with cutaneous symptoms while undergoing treatment with advanced therapies.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000001625

Authors: Luis E. Ospina Velasquez, Konstantinos A. Papadakis, Siri A. Urquhart

Institution: Mayo Clinic

Language: English

Topic: Vasculitis and related conditions

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408163055

FWCI: 1.762

Cites: 12

Cited by: 3

Related to: 10