Endocarditis and Hypertrophic Cardiomyopathy
Year: 2025
Type: article
Study design: Case Report
Abstract: Infective endocarditis (IE) is an uncommon but potentially fatal complication in patients affected by hypertrophic cardiomyopathy (HCM). The risk has been described to be significantly higher than in the general population, but the incidence of IE in HCM population remains unknown. The complex pathophysiology of this disease, characterized by structural alterations of the mitral valve apparatus and the presence of turbulent flow that promotes the deposition of microorganisms, could provide a substrate for IE and may, to some extent, explain its higher incidence in this specific population. The purpose of this case series is to highlight the correlation between endocarditis and HCM, a concern that has also been raised in recent European guidelines.
Source: JACC Case Reports
Authors: Sebastiano Bertola, Davide Margonato, Alessandra Roccabruna, Martina Belli, Alessandro Malagoli, Martina Setti, Federica Ilardi, Matteo Lisi, Giulia Elena Mandoli, Maria Concetta Pastore, Simona Sperlongano, Marco Matteo Ciccone, Saverio Muscoli, Eustachio Agricola, Giovanni Benfari, Matteo Cameli, Antonello D’Andrea
Institutions: University of Verona, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, University of Modena and Reggio Emilia, University of Naples Federico II, Ospedale "Santa Maria delle Croci" di Ravenna, University of Siena, University of Campania "Luigi Vanvitelli", University of Bari Aldo Moro, Policlinico Tor Vergata
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $850
OpenAlex ID: W4408166034