Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions
Year: 2025
Type: article
Abstract: A novel fluorine containing Schiff base tert-butyl 3-(((2-hydroxynaphthalen-1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1-carboxylate (RSB1) a possible potent reactive building block was synthesized by condensing fluorine bearing piperidine containing boc protected amine derivative with the 2hydroxy napthaldehyde using simple condensation method in good yield and high purity. Structure characterization of the title compound was done by, 1H-NMR, 13C-NMR and HRMS spectral analysis
Authors: Pruthviraj K., Sunil K.
Institution: Sri Siddhartha Academy of Higher Education
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4408176476