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Sickle Cell Disease and Cardiovascular Damage: Understanding the connection and straregies for prevention

Year: 2024

Type: article

Abstract: Introduction: Cardiovascular alterations contribute to the morbidity of adult patients with sickle cell disease, as a clinical expression of chronic organ damage. Sickle cell disease is a generic term assigned to a group of genetic disorders characterizedby a predominance of hemoglobin S(HBS) and clinically expressed in homozygous or doublé heterozygous patients. Development: Alterations in cardiac morphology and function were identified from the earliest cases of sickle cell disease. The prevalence of cardiac involvement in adult patients with sickle cell disease has been estimated to be as high as 82%. Conclusions: Patients with sickle cell disease exhibit a high prevalence of cardiovascular alterations, including the need for regular cardiovascular monitoring in this population.

Source: Health Leadership and Quality of Life

DOI: 10.56294/hl2024.667

Authors: Anelys García Salgado García Salgado, Olga Margarita Agramonte Llanes, Anadely Gámez Pérez

Institutions: Universidad de Ciencias Médicas de la Habana, Instituto de Hematología e Inmunología

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408177286

FWCI:

Cites: 8

Cited by:

Related to: 10