Work

Not All Heart Failure Improves With Diuresis: A Lesson in Left Ventricular Assist Device Physiology

Year: 2025

Type: article

Abstract: Although heart transplantation is considered the optimal therapy for end-stage heart failure, there are not enough donors to meet the rising demand. For patients with refractory heart failure who require additional hemodynamic support, left ventricular assist devices (LVADs) may be an option. Transthoracic echocardiography (TTE) remains the initial modality of choice for routine LVAD evaluation and speed optimization. On the basis of clinical trial data, 25% of patients with continuous-flow LVADs experience New York Heart Association class II to IV symptoms, likely due, in large part, to inadequate left ventricular unloading.

Source: CASE

DOI: 10.1016/j.case.2025.01.003

Authors: Giancarlo Saldana, Steve Mazzone, Kyle Hipke, Mark N. Belkin, Karima Addetia

Institution: University of Chicago

Language: English

Topic: Mechanical Circulatory Support Devices

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $950