Work

Isoflavone Constituents of the Underground Parts of Iris florentina and Their Inhibitory Activity on the Formation of Advanced Glycation End Products

Year: 2025

Type: article

Abstract: Two new isoflavone glucosides, irisolone 4'-O-[O-β-d-glucopyranosyl-(1→6)-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside] (1) and iriskashmirianin 4'-O-[O-β-d-glucopyranosyl-(1→6)-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside] (2) were isolated from the underground parts of Iris florentina (Iridaceae). The structures of 1 and 2 were determined based on extensive spectroscopic data analyses and hydrolytic cleavage results. The isoflavone derivatives previously isolated from this plant were evaluated for their ability to inhibit the formation of advanced glycation end products.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.c24-00776

Authors: Yuka Yoshizawa, Nana Fujita, Akihito Yokosuka, Yoshihiro Mimaki

Institution: Tokyo University of Pharmacy and Life Sciences

Language: English

Topic: Phytochemistry and Biological Activities

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: diamond

Funder: Japan Society for the Promotion of Science