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A Case of Rectus Sheath Hematoma Caused by Self-Injection of Certolizumab Pegol

Year: 2025

Type: article

Abstract: Rectus sheath hematoma (RSH) is a condition caused by hemorrhage into the rectus sheath. A 61-year-old man with end-stage renal failure and rheumatoid arthritis presented to our hospital with abdominal pain. The patient had been receiving biweekly self-injections of certolizumab pegol to the abdominal wall. Computed tomography (CT) demonstrated a large high-density left-sided RSH. Abdominal pain gradually exacerbated; thus, transcatheter arterial embolization (TAE) for the left inferior epigastric artery (IEA) was performed. This is the first reported case of RSH caused by certolizumab pegol. Factors contributing to RSH include low abdominal wall fat, the use of auto-injector-based preparations, and anticoagulant use in dialysis.

Source: Cureus

DOI: 10.7759/cureus.80154

Authors: Atsuhiko Suenaga, Yuka Hashimoto, Akiko Kanaya, Kennichi Fukunari, Yasuhiro Kawahara, Motoaki Miyazono

Institutions: National Hospital Organization, Ureshino Medical Center, Saga University, Sasebo Kyosai Hospital

Language: English

Topic: Case Reports on Hematomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408185241

FWCI: 0.892

Cites: 19

Cited by: 1

Related to: 10