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Psychedelics for Substance Use Disorders: Updates for the Psychiatric Trainee

Year: 2025

Type: article

Abstract: Psychedelics have recently gained attention as potential therapeutic agents for treating patients with substance use disorders, with studies showing promise of psychedelics for reducing substance use and cravings. Despite a limited number of well-controlled modern trials examining psilocybin treatment for alcohol or tobacco use disorder, the available evidence suggests that many serotonergic psychedelics may have benefits for managing various substance use disorders. In this narrative review, the authors aimed to critically evaluate the literature on the use of psychedelics for substance use disorders, including evidence for their efficacy, safety, and potential risks.

Source: American Journal of Psychiatry Residents Journal

DOI: 10.1176/appi.ajp-rj.2025.200301

Authors: Lauren Wilseck, Preet Chatha, Lawrence Canale, Dhvanit Raval, Jeremy Weleff

Institutions: Kansas City University, Yale University

Language: English

Topic: Psychedelics and Drug Studies

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408204973

FWCI:

Cites: 22

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Related to: 10