Year: 2025
Type: article
Study design: Case Report
Abstract: Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness caused by antibodies targeting acetylcholine receptors (AChRs) or muscle-specific kinase (MuSK). Double-seropositive MG (DSP-MG) caused by both antibodies is rare. We herein report a 78-year-old woman who developed DSP-MG after coronavirus disease 2019 infection. She presented with neck muscle fatigue and upper-limb weakness. Elevated levels of anti-AChR and anti-MuSK antibodies were detected. The patient responded well to the immunosuppressive therapy. This case highlights the potential for various autoimmune neurological conditions post-viral infection and the significance of prompt recognition and treatment.
Source: Internal Medicine
Authors: Yuki Hiraoka, Yasushi Hosoi, Takuya Tsubata, Miharu Yanagida, Yusuke Otake, Michiko Ito
Institution: Hamamatsu Medical Center
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408215279