Work

Acute Coronary Syndrome in a Young Woman With Takayasu Arteritis and Pancoronary Aneurysms

Year: 2025

Type: article

Abstract: BACKGROUND: Takayasu arteritis (TA) is a rare vasculitis affecting large vessels, predominantly in young women. Coronary artery involvement, although uncommon, significantly worsens the prognosis due to complications (eg, aneurysm formation, thrombosis), potentially leading to acute myocardial infarction. CASE SUMMARY: A 27-year-old woman presented with fever, fatigue, and conjunctival erythema. One month later, she developed acute chest pain and dyspnea. Coronary angiography revealed giant coronary ectasia with right coronary artery thrombosis, and noninvasive imaging confirmed TA. The patient was treated with immunosuppressive therapy, antithrombotic agents, and multidisciplinary care, resulting in significant clinical improvement. TAKE-HOME MESSAGE: TA with coronary involvement, particularly coronary aneurysms, is an extremely rare but clinically significant condition.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2024.103030