79P Prospective study of endocrine effects and quality of life in paediatric and young CML patients on tyrosine kinase inhibitors: An experience from a tertiary care centre in India
Year: 2025
Type: article
Study design: Observational Study
Abstract: Chronic myeloid leukaemia (CML) is a rare form of childhood cancer, accounting for just 2-3% of paediatric leukaemia’s. While the introduction of tyrosine kinase inhibitors (TKIs) has significantly improved treatment outcomes, their long-term impact on endocrine functions and quality of life (QoL) in children is still not fully understood. This study investigates the off-target effects of TKIs on growth, bone health, metabolism, and QoL in paediatric CML patients.
Source: ESMO Open
Authors: R.M. Nannapaneni, D. Pushpam, A. Kumar, R. Khadgawat, S. Bakhshi, C. Nagpal, S.U. Parampalli
Institution: All India Institute of Medical Sciences
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,910
OpenAlex ID: W4408218176