The establishment of local diagnostic reference levels for computed tomography cerebral angiography in Jeddah city of Saudi Arabia
Year: 2025
Type: article
Study design: Observational Study
Abstract: Purpose Cerebral computed tomography angiography (CTA) is a useful imaging modality for the diagnosis of blood vessels in brain diseases. The aim of this study was to assess the radiation dose and risk estimation for cerebral CTA scans for adult patients and introduce local diagnostic reference levels (LDRLs) for cerebral CTA patients. Methods In this retrospective study, 291 patients (194 male and 97 female) underwent cerebral CTA scans of the head. The dosimetric quantities of the CT dose index volume (CTDIvol) and the dose length product (DLP) were collected. Following this, the effective dose, cancer risk and genetic risks were calculated. CTDIvol and DLP were derived; the suggested LDRLs were determined based on the 75th percentile for all examinations. Results The mean patient dose values for CTDIvol, DLP and effective dose were 42.83 ± 1.98 mGy, 1691.76 ± 128 mGy·cm and 5.20 ± 0.39 mSv, respectively. The CTDIvol value was the same for both sexes, while the DLP and effective dose values for males were 4% higher than for females. The cancer risk value for cerebral CTA was 29 × 10−5 ± 3.2 Sv−1, and the genetic risk was 10 × 10−4 ± 1.2 Sv–1. The LDRL value for CTDIvol was 32.36 (mGy) and for DLP was 1266.25 (mGy.cm). Conclusion This study assessed the radiation doses for cerebral CTA scans and introduced local DRLs for cerebral CTA examinations. In this study, the DLP and effective dose values were higher than those of other studies. The procedure of cerebral CTA scans that include total head and neck area should be optimized in regard to scan length and the head and neck k-factor. Therefore, it is highly recommended to establishing regional and national DRLs.
Authors: Khadijah khan, Afnan Al-Harbi, Alaa Fallatah, Mohamed Alasmary, Younis Bokhary, Marwan Alhazmi, Saeed Al-Qahtani, Abdulwali Ajlouni, Emtenan Alotaibi, Ali Alomari, Marwan Althomali, Merfat Algethami, Omemh Bawazeer
Language: English
Topic: Radiation Dose and Imaging
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4408218566