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Role of transbronchial lung cryobiopsy in diagnosing pulmonary alveolar proteinosis—a five-case series

Year: 2025

Type: article

Abstract: Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disease marked by the accumulation of PAS-positive proteinaceous material within distal airspaces. Diagnostic procedures include bronchoalveolar lavage, transbronchial lung biopsy (TBLB), and surgical lung biopsy (SLB). Recently, transbronchial lung cryobiopsy (TBLC) has emerged as a promising technique for diagnosing parenchymal lung diseases. This case series investigates the efficacy of TBLC in diagnosing PAP and compares it to traditional TBLB methods.

Source: Egyptian Journal of Bronchology

DOI: 10.1186/s43168-025-00377-3

Authors: Vimal Raj Ramachandran, Hsu-Yuan Chen, Yu-Chu Kuo, Wen-Chien Cheng, Biing-Ru Wu, Wei-Chih Liao, Chia-Hung Chen, Chih-Yen Tu

Institutions: Mahatma Gandhi Medical College and Research Institute, China Medical University, Sri Balaji Vidyapeeth University, China Medical University Hospital, National Chung Hsing University

Language: English

Topic: Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408219179

FWCI: 0.591

Cites: 7

Cited by: 1

Related to: 10