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Intrahepatic cholangiocarcinoma: correlation between histological subtype and survival

Year: 2025

Type: article

Abstract: Aim. To study the pathological histological subtypes of intrahepatic cholangiocarcinoma and their impact on survival. Materials and methods. The study involved the analysis of perioperative data from 65 patients with intrahepatic cholangiocarcinoma. Among them, 32 patients (49%) were found to have the small bile duct subtype, while 33 patients (51%) were diagnosed with the large bile duct subtype. Results. The histopathological subtype of intrahepatic cholangiocarcinoma originating from large bile ducts is considered to be a significant factor affecting overall survival (p < 0.0001) and disease-free survival (p =0.0074). Conclusion. In clinical practice, assessing the small and large duct subtypes of intrahepatic cholangiocarcinoma is claimed to be essential for stratifying risk factors affecting disease prognosis.

Source: Annaly khirurgicheskoy gepatologii = Annals of HPB surgery

DOI: 10.16931/1995-5464.2025-1-31-38

Authors: M. G. Efanov, N. S. Karnaukhov, N. N. Britskaia, N. V. Makarenko, P. V. Tarakanov, D. V. Fisenko, V. V. Tsvirkun

Institution: Moscow Clinical Scientific Center

Language: English

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408219894

FWCI:

Cites: 22

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Related to: 10