Work

Unexplained Gastric Ulcer: Role of Cinacalcet

Year: 2025

Type: article

Abstract: or impaired mucosal defense mechanisms against acid exposure by medications such as non-steroidal anti-inflammatory drugs (NSAIDs). Hypercalcemia can present with peptic ulcer-related symptoms, and cinacalcet is an effective medical treatment for primary hyperparathyroidism (PHPT) for non-surgical candidates. We present a case of a 66-year-old male patient with a history of primary hypercalcemia as a result of hyperparathyroidism, on chronic cinacalcet, who was found to have gastric ulcers on endoscopy. After the reduction of the cinacalcet dose in one year, there was a complete resolution of inflammation in the gastric body.

Source: Cureus

DOI: 10.7759/cureus.80226

Authors: Christine Son, Joshua Kalapala, Jeff Leya, Nirmal Desai, Promila Banerjee

Institutions: Loyola University Medical Center, Loyola Medicine, Loyola University Chicago, Edward Hines, Jr. VA Hospital

Language: English

Topic: Parathyroid Disorders and Treatments

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4408231632