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Modern approaches to the application of radiation research methods for visualization of the glymphatic system of the brain

Year: 2025

Type: article

Abstract: The glymphatic system of the brain plays an important role in removing metabolic waste and maintaining the homeostasis of the central nervous system. Disorders of its functioning are associated with the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Modern methods of radiation diagnostics, including contrast-enhanced magnetic resonance imaging (MRI), functional MRI, and diffusion-weighted imaging, allow us to study the dynamics of cerebrospinal fluid flow and glymphatic clearance processes. This article discusses current approaches to the visualization of the glymphatic system, their diagnostic capabilities and prospects for application in clinical practice.

Source: Russian Journal for Personalized Medicine

DOI: 10.18705/2782-3806-2025-5-1-50-57

Authors: D. A. Beregovskii, Ya. A. Filin, A. M. Klimovich, D. D. Dorohova, G. E. Trufanov

Institution: Federal Almazov North-West Medical Research Centre

Language: English

Topic: Cerebrospinal fluid and hydrocephalus

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4408236137

FWCI:

Cites: 27

Cited by:

Related to: 10