Challenges in Diagnosing Parkinson's Disease vs. Multiple System Atrophy: A Case Report Highlighting MRI as a Key Diagnostic Tool
Year: 2025
Type: article
Study design: Case Report
Abstract: We report a case that outlines the diagnostic challenge faced in differentiating between Parkinson's disease (PD) and multiple system atrophy (MSA) in a 58-year-old man with a history of PD. Despite treatment, the patient exhibited limited response and presented with symptoms suggestive of atypical Parkinsonism, prompting a brain MRI. The MRI revealed characteristic features of MSA, showing putaminal atrophy and altered signal intensity. Differential diagnosis between MSA and PD is crucial, with specific MRI findings serving as key differentiators. Early recognition and differentiation are vital for appropriate management.
Source: Nepalese Journal of Radiology
Authors: Ongden Yonjen Tamang, Santosh Maharjan, Rudra Prasad Upadhyaya, Ashish Shrestha, Gaurab Shrestha, Rajiv Chaudhary
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4408239047