Treatment of Haemophilus influenzae Serotype A (Hia) Meningitis in a Pediatric Patient: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: serotype A (Hia) meningitis is a rare but severe pediatric infection, with significant risks of mortality and long-term complications. Here, we describe a 10-week-old male presenting with Hia meningitis complicated by cerebritis, seizures, and central venous catheter-related deep vein thrombosis (CADVT). The patient initially presented with fever, irritability, and feeding difficulties and was later found to have significant laboratory abnormalities and cerebrospinal fluid (CSF) findings suggestive of bacterial meningitis. This case highlights the empiric treatment of pediatric meningitis, tailored and adjunctive treatments based on culture results, and other thrombotic and neurological complications. Despite high morbidity risks, the patient demonstrated complete clinical recovery at two years and showed no signs of long-term sequelae. This case emphasizes the evolving epidemiology of Hia and the importance of timely diagnosis and multidisciplinary management in severe pediatric infections, to ensure the minimization of negative externalities.
Source: Cureus
DOI: 10.7759/cureus.80253
Authors: Matthew Thomas, Shivang Patel, Harthik Kambhampati, Miriam Thomas
Institution: Lake Erie College of Osteopathic Medicine
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4408248940